18 persons have been picked up by police in a row between two groups at Dagomba Line in Kumasi in the Ashanti region
Persons involved in the clashes were seen firing gunshots while others held machetes.
A reinforcement team of police and military officers have been dispatched to the area as structures have been set ablaze by the feuding factions.
Some victims of the violence have sustained machete wounds.
Some residents have fled their homes over fears of losing their lives.
Reports earlier revealed that relatives calm had returned to the area after the initial clashes got seven injured.